比尔和梅林达盖茨基金会;美国国家过敏和感染性疾病研究所基金项目N01AI90500C;国际科技合作与交流重大专项2014DFA30340;河南省重点科技攻关项目152102310152;河南省医学科技攻关项目201702292;Bill and Melinda gates foundation;National Institute of Allergy and Infectious Diseases fundingN01AI90500C;Major International Science and Technology Cooperation2014DFA30340;Key Scientific and Technological Project of He'nan Provincial152102310152;He'nan Medical Science and Technology attach plan project201702292