江苏省科技计划项目基金项目BE2016699;南通市前沿与关键技术社会民生创新计划基金项目MS22015072;“十三五”科教强卫工程南通市青年医学重点人才基金项目025;南通市卫健委青年基金项目WKZL201815Technology and Science Foundation of Jiangsu ProvinceBE2016699;Frontier and Key Technology Social Welfare Innovation Project Nantong UniversityMS22015072;" 13th five-year" Science,Education and Health Project Nantong Youth Medical Key Talents Project025;Nantong Health Commission Youth Fund ProjectWKZL201815